Rheumatology
Written on 01/01/2025What are the key differences between anti-centromere and anti-scleroderma 70 antibodies in scleroderma, and how do they impact diagnosis and prognosis?
Scleroderma, a complex autoimmune disease, presents diagnostic and prognostic challenges. Understanding the roles of anti-centromere and anti-scleroderma 70 (anti-topoisomerase 1) antibodies is crucial for effective management. This post will delve into their key differences and clinical implications. Read more
Written on 02/07/2025What is ANCA-associated vasculitis, how does it damage blood vessels, and what are the key treatments for this autoimmune condition?
ANCA-associated vasculitis is a group of autoimmune diseases characterized by inflammation of small and medium-sized blood vessels. This inflammation, or vasculitis, can lead to significant damage, potentially causing tissue ischemia and aneurysms. The presence of anti-neutrophil cytoplasmic antibodies (ANCA) in the blood is a hallmark of these conditions. Read more