Pre-Medical Studies

Written on 02/27/2025

How Do You Determine R vs S Configuration of a Chiral Carbon Based on Atomic Priority and Spatial Arrangement?

In organic chemistry, understanding the spatial arrangement of atoms in a molecule is crucial, especially when dealing with chiral molecules. Chiral carbons, those bonded to four different substituents, can have two non-superimposable mirror images called enantiomers. To distinguish between these enantiomers, we use the R/S system of absolute configuration. But how exactly do we determine if a chiral carbon is R or S? Read more